Coagulation activity and emboli counts in patients with prosthetic cardiac valves.

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Coagulation activity and emboli counts in patients with prosthetic cardiac valves.

BACKGROUND AND PURPOSE The underlying embolic material detected by transcranial Doppler ultrasound in patients with prosthetic heart valves remains unknown. We undertook this study to evaluate the relation between the number of Doppler emboli signals and the activity of the coagulation system. METHODS Patients with various types of prosthetic valves (n = 120) and patients in atrial fibrillati...

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Pregnancy in patients with prosthetic heart valves.

Pregnancy and delivery were analyzed in 23 women one to ten years after undergoing prosthetic heart valve replacement. The main points of management during pregnancy and delivery were cardiac management and management against thromboembolism. The functional status of the pregnant patients was grade I of the New York Heart Association criteria in eight, grade II in 13 and grade III and higher in...

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Coagulation activation is associated with interleukin-6 plasma levels in patients with mechanical prosthetic heart valves.

BACKGROUND The intensity of oral anticoagulant therapy in patients with mechanical heart valves is evaluated and controlled by the International Normalized Ratio (INR). However, intravascular coagulation activation can occur despite normal INR values and is related to clinical events. Here, anticoagulation efficiency was assessed by sensitive techniques and potential determinants of coagulation...

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ژورنال

عنوان ژورنال: Stroke

سال: 1994

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.25.6.1211